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Marburg virus : ウィキペディア英語版
Marburg virus

Marburg virus ( 〔) is a hemorrhagic fever virus of the Filoviridae family of viruses and a member of the species ''Marburg marburgvirus'', genus ''Marburgvirus''. Marburg virus (MARV) causes Marburg virus disease in humans and nonhuman primates, a form of viral hemorrhagic fever.〔(【引用サイトリンク】first1=Anna )〕 The virus is considered to be extremely dangerous. The WHO rates it as a Risk Group 4 Pathogen (requiring biosafety level 4-equivalent containment).〔(【引用サイトリンク】title=Biosafety in Microbiological and Biomedical Laboratories (BMBL) 5th Edition )〕 In the United States, the NIH/National Institute of Allergy and Infectious Diseases ranks it as a Category A Priority Pathogen〔(【引用サイトリンク】title=Biodefense and Emerging Infectious Diseases )〕 and the Centers for Disease Control and Prevention lists it as a Category A Bioterrorism Agent.〔(【引用サイトリンク】title=Bioterrorism Agents/Diseases )〕 It is also listed as a biological agent for export control by the Australia Group.〔(【引用サイトリンク】title=List of Biological Agents for Export Control )
In 2009, expanded clinical trials of an Ebola and Marburg vaccine began in Kampala, Uganda.〔Beth Skwarecki (Ebola, Marburg DNA Vaccines Prove Safe in Phase 1 Trial ) Medscape Medical News, September 17, 2014〕〔(Evaluating an Ebola and a Marburg Vaccine in Uganda ) U.S. Department of Health & Human Services

==Discovery==
Marburg virus was first described in 1967. It was noticed during small outbreaks in the German cities Marburg and Frankfurt and the Yugoslav capital Belgrade in the 1960s. German workers were exposed to tissues of infected grivet monkeys (''Chlorocebus aethiops'') at the city's former main industrial plant, the Behringwerke, then part of Hoechst, and today of CSL Behring. During these outbreaks, 31 people became infected and seven of them died. MARV is a Select Agent. 〔(【引用サイトリンク】title=National Select Agent Registry (NSAR) )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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